Medication Suggestions

Some families report that the following medications have been useful for their child with MECP2 Duplication Syndrome. Many of these medications must be prescribed by a physician and are not available without a prescription. Families considering the use of any of these medications should discuss the potential risks and benefits with their child's physician. It is also important to note that while some of these medications worked well for some children, other MECP2 Duplication children did not respond well to the drug. Even though our children share the same syndrome, not all respond to medications in the same way.

Regulate Sleep

Miralax, Restoralax, Movicol (polyethylene glycol 3350)
Forlax (macrogol 4000, polyethylene glycol 4000)
Lactulose (others noted this to cause extreme gas)
Microlax micro-enema (sodium citrate and sodium lauryl sulphoacetate)

Acid Reflux and Heartburn
Ranitidine (Zantac, Raniplex)
Prevacid (lansoprazole)
Nexium (esomeprazole)
Gaviscon (sodium alginate)
Prepulsid (cisapride) *This medicine can be dangerous for the user. The doctor needs to do tests before and after.
Losec (omeprazol)

For Teeth
Zymafluor (sodium fluoride)

Prevents Yeast Growth and Diarrhea (due to antibiotic use)

Nasal Congestion
Flonase (luticasone propionate)
Nasonex (mometasone furoate)

Stuffy Nose
Saline Spray
Vicks plug in vapor pads

Singular (montelukast) this works for some and has caused drop seizures in another.
Xyzal (levocetirizine)
Allergy Shots
Nasonex (mometasone furoate)

albuterol , salbutamol (Ventolin) neb treatments (this works for some and others get wired and hyper from it)
Xopenex (levalbuterol HCl)
Mucamist (acetylcysteine)
Hypertonic Saline Solution
Pulmicort (budesonide)
Qvar (Beclomethasone Oral Inhalation)
Flovent (fluticasone inhalation)
Clarythromycin (antibiotic for chest infections)

Keppra (Levetiracetam) *a significant difference was noted between genetic and brand name Keppra.
Tegretol (Carbamazepina or Carbemazepne)
Banzel (Inovelon, Rufinamide)

Neurontin (gabapentin)
Depakote, Epival (divalproex sodium)
Diastat (Emergency Seizure Medicine to keep on hand even if child doesn’t have seizures yet)

Prophylactic to Prevent Infection
Septra (trimethoprim and sulfamethoxazole)
Zithromax (azithromycin)

Focalin (dexmethylphenidate)

Fragile Bones
Vitamin D

Autonomic Dysfunction
Hydrocortison (hydrocortisone)

Prevention of Aspiration of Fluids
Thick It
Simply Thick